Scientific journal NRU ITMO
Series "Processes and Food Production Equipment"
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ISSN:2072-2389

SEPTEMER 2012 (published: 01.09.2012)

Number 2(14)

Home > Issue > Inhibition aminotransferase muscle tissue with aromatic acids, hydrazides

UDC 637.5.04/.07

Inhibition aminotransferase muscle tissue with aromatic acids, hydrazides

Blandov A.N., Shleykin A.G.

It was studied in vitro experiments the kinetics of inhibition of muscle tissue enzyme alanine aminotransferase by hydrazides of aromatic carboxylic acids. The competitive mechanism of enzyme inhibition was shown by Lineweaver-Burke plot. Benzhydrazide was more potent inhibitor than salicylhydrazide
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Keywords: alaninaminotranspherase, competitive inhibition, hydrazides of aromatic carboxylic acids.

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